Why Bird Flu Has Been Kept at Bay

February 13th, 2008

Now that they know why bird flu isn’t readily transmissible from human to human, how long until a weaponized version is engineered?

That’s me being optimistic; assuming that a weaponized form doesn’t exist already.

Via: BBC:

Scientists say they have identified a key reason why bird flu has so far not posed a widespread menace to humans.

So far, the H5N1 strain has mainly infected birds and poultry workers, but experts fear the virus could mutate to pass easily from human to human.

However, Massachusetts Institute of Technology found that to enter human respiratory cells the virus must first pick a very specific type of lock.

The study appears in the journal Nature Biotechnology.

The researchers say their discovery may help scientists better monitor changes in H5N1 – and find better ways to fight it.

Flu viruses attack by binding sugar chains, called glycans, that line the airways and lungs.

Latching on

The chemical linkages between the sugar molecules in these chains differ between humans and birds.

Until now it has been assumed that bird flu viruses would be adapt to humans simply by acquiring mutations that enable them to attach to the human types.

But Dr Ram Sasisekharan and colleagues found this step depends on the shape assumed by the flexible sugar chains rather than the type of linkage.

Bird flu viruses currently require cone-shaped glycans to infect birds, so the umbrella shape found in humans has protected most of us from avian flu.

This suggests that for the H5N1 bird flu virus to become pandemic it must adapt so that it can latch onto the umbrella-shaped glycans of the human upper respiratory tract.

Dr Jeremy Berg of the National Institutes of Health which funded the work said: “Sasisekharan’s team has changed our view of flu viruses and how they must adapt to infect us.

“The work may also improve our ability to monitor the evolution of the H5N1 virus and thwart potential outbreaks.”

Professor Ian Jones, professor of virology at the University of Reading, said: “This new work shows that there are sublevels of sugar that the virus prefers to use to get into cells and the authors suggest this is a significant factor in why H5N1 has not yet spread to humans.

“It provides a finer level of analysis than has been done so far but it is likely that other factors, like the reduced temperate of the human upper airway, also are involved.”

Research Credit: Samadhisoft

Posted in Kill Off | Top Of Page

5 Responses to “Why Bird Flu Has Been Kept at Bay”

  1. es says:

    Did you know that a virus is not a living organism, that is, it does not meet the criteria for the definition of life? This is not disputed; just check wikipedia. A virus is no more than dna-material in a capsule of proteines. Its biological function is unknown, but has been postulated to function as a means of communication between cells.

    Did you know that:
    – the existence of a bird flu virus has not been publicly proven? No joke, it is a hypothetical virus; bird flu tests, test for the presence of particles presumed to belong to bird flu virus, not for the actual virus.
    – the existence of the hiv virus has not been proven? Similarly, hiv-tests do not test for hiv?
    – long term safety and efficacy of any vaccine against a virus has ever been proven?

    I dove into this subject about two years ago, and was amazed by the vast amount of junk-science. My best guess is that viruses simply do not cause disease. They are merely a symptom of disease. Think about it.

    Bird flu is a means of economical warfare, so is Aids, so is vaccination (which I guess are also a form of low-intensity chemical warfare through pharmaceuticals).

    Check the following references;

    on Bird flu
    http://www.whale.to/vaccines/rappoport34.html
    http://rolf-martens.com/otherspubs/051027_interview_s_lanka_on_bird_flu_etc.html
    http://www.scoop.co.nz/stories/HL0511/S00351.htm

    on Aids
    http://aras.ab.ca/
    http://www.theperthgroup.com/
    http://www.sparks-of-light.org/HIVGATE%20-%20review%20copy.pdf
    http://hivskeptic.wordpress.com/

    on Vaccination
    http://chetday.com/vaccinationmyths.htm
    http://www.thinktwice.com/
    http://www.healthsentinel.com/graphs.php

  2. Miraculix says:

    ES…

    That was perhaps THE most on-target reply to a topic thread I have read on Cryptogon.

    The term everyone should start with, aside from all the excellent links listed above, is:

    PLEOMORPHISM

    In a nutshell, Pasteur was wrong. Many have been the physicians who’ve risked their careers to advance the body of evidence proving that Louis Pasteur’s “germ theory” is STILL wrong, a long and distinguished list echoing the “pleomorphic theory” originally developed by the highly respected Professor Antoine Béchamp, a 19th century competitor of Pasteur, as well as his contemporary Claude Bernard. Pasteur eventually admitted the truth, stating on his death-bed that “Bernard was right… the microbe is nothing; the terrain is everything.”

    Béchamp and other scientists suspected a microbe could evolve through many structural forms, from virus to bacterium to yeast to fungus to mold, as well as de-evolving back into a proto-virus. Béchamp examined this process closely under his microscope. Bernard expounded on the theory, explaining that the state of the inner terrain — the “milieu interieur” — was the actual cause of disease, rather than the microbes themselves. Béchamp, Bernard and a host of other notables in the scientific community vehemently opposed germ theory, advocating instead a theory of pleomorphism, stating that:

    · Acidic terrain, not the germs themselves, cause disease.
    · Germs are present in the body in vast quantities at all times and don’t have to enter the body (although this also happens).
    · Blood is not sterile and can contain many microbial forms.
    · Germs are pleomorphic, i.e., they can evolve through multiple forms.
    · Virtually all diseases are caused by acidic terrain.
    · Diseases can be prevented and reversed by increasing the alkalinity of the terrain.

    They discovered that acidic blood and tissue provide ideal terrain for disease to develop. As the milieu becomes increasingly acidic, microbes evolve into pathogenic forms to carry out the work nature designed them for: as cleaners and undertakers, scavenging and consuming inflamed or infected tissue. A stasis machine, the human body does all it can to maintain a slightly alkaline blood pH of 7.365, even stripping reserves like calcium from the bones to buffer a rise in acidity — and leading to the condition labeled by modern medicine as “osteoporosis”. As blood pH drops, even just 0.1, the increase in acidity is interpreted by microbes already present in the body as a sign of a dead or dying body. This prompts them to morph from benign bacteria into virulent yeasts and molds that can reduce the body back to the dust from whence it came.

    Disease simply cannot take firm hold in a properly alkaline body, and an alkalising diet and lifestyle can prevent and reverse disease. But don’t expect to hear this concept endorsed by orthodox medicine any time soon — there’s not as much filthy lucre to be made via radical surgery, toxic chemotherapy and catalyzing irradiation.

  3. Eileen says:

    Miraculix,
    Wish I’d read this earlier than now. I know I can go do research, but do you know of the way to alkalise the body?
    I bought Mom alkaline water when she came home from the hospital a month ago. Worked wonders.
    What else to do.
    Thanks,
    E

  4. Kevin says:

    @ Eileen

    Absolutely, look at the diets that alkalize the body, however, for additional help in urgent situations, type cesium chloride into your favorite search engine.

  5. il says:

    Eileen, don’t forget Apple Cider Vinegar for alkalizing!

    Speaking of acid conditions and disease, has anyone read or heard about Dr Tullio Simoncini, who believes that cancer = the fungus Candida albicans? See http://www.nexusmagazine.com/articles/CancerIsAFungus.html for more details and links.

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