The Computer that Runs on Human Neurons

April 6th, 2025

I’ve posted about this before. I think it’s worth monitoring closely because my guess is that this (or something like it) is how a disorderly advance in AI could happen.

Via: El País:

Lab-grown brain cells are the basis for the functioning of the CL1, which has been announced as the first commercially-sold biological computer. This machine promises to unravel information-processing in the brain. The CL1 has been designed for the purpose of drug development, by studying how neurons react to certain compounds. It will also help scientists and medical laboratories understand how neurons process information and how real-time learning works. The computer will also offer insight into the mechanisms that trigger some neurodegenerative and cognitive diseases.

“We think that, since we’re experiencing a push for computers to have artificial intelligence, then there really must be an interest in understanding how intelligence arises, which is biological in origin. Because the only generalized intelligence we know of is that of humans and animals,” says Hon Weng Chong, in a video call with EL PAÍS. He’s the founder and director of Cortical Labs, the Australian company that’s behind the new device.

“When neurons are cultured, they typically don’t receive data; they’re simply arranged in a dish, emitting and collecting their own electrical activity. But that’s not what actually happens naturally inside a living being. So, we created a system that allows us to build simulations that neurons can process,” Chong explains.

To keep this hybrid organism alive, the CL1 has an internal structure that regulates the flow of gases, pumps and temperature. The device has a futuristic design, with a rectangular shape and a weight of almost 13 pounds. It measures just over 20 inches long and six inches wide. The top is transparent, allowing you to see the cables and tiny tubes that make the computer work. On the front, a touchscreen provides information about the system’s status, such as temperature.

The cells are fed a nutrient-rich solution that reaches them through filtration units. Specifically, two filtration cartridges, with a membrane that separates clean fluid from waste. Since some proteins are trapped in the membrane, maintenance is required every six months to prevent the neurons from dying.

“We try to mimic what the body does: keep them well-nourished, eliminate waste and keep them at the right temperature. It shouldn’t be too hot or too cold, around 37 degrees Celsius [98ºF], which is body temperature. We also have to maintain the correct pH levels, so it’s neither too acidic nor too alkaline,” Chong details.

On the operational side of things, the CL1 operates with a biological intelligence system called bioS, which allows users to execute code through neurons and perform computing tasks. The connection between the organic and technological parts is achieved through a microprocessor that acts as an interface, receiving and sending electrical impulses to the nerve cells.

One Response to “The Computer that Runs on Human Neurons”

  1. Snowman says:

    Is this worse than cannabalism? I’d say yes.

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